"So how do you explain the increased risk of high-grade disease reported in 2003?
There are two mechanisms by which we believe finasteride enhances the detection of high-grade cancer on prostate biopsy.
First, finasteride is known to decrease the size of the prostate gland by about 25%. When you biopsy a smaller gland, you are more likely to sample an area of cancer—or high-grade cancer—with your biopsy needle, compared to doing the same biopsy in a larger gland.
Second, as we showed in another analysis of the PCPT, finasteride improves the sensitivity of the PSA test for the detection of overall and high-grade prostate cancer. Because the decision to perform prostate biopsies during the study was based on PSA levels, this may have contributed to increased detection of prostate cancer, in general, and high-grade prostate cancer, in particular, among men receiving finasteride.
Due to the effects of this drug on gland size and PSA performance, it seems quite likely that the PCPT not only overestimated the harm of finasteride in terms of the observed increase in high-grade cancer, but may have underestimated the benefit of finasteride in terms of the amount of reduction in prostate cancer risk."
Kanser üzerine kurulu bir yabancı siteden aldım. İngilizesi olan okusun olmayan çevirsin okusun.
https://www.cancer.gov/news-events/cancer-currents-blog/2019/prostate-cancer-prevention-finasteride-parnesYapsa bile çaya attığımız şeker, kahveye attığımız süt tozundan daha masumdur diye düşünüyorum. En basitinden korona geçirenlere bile, organlarında kalıcı hasar oluşuyor diyorlar. Atsan bir dert atmasan bir dert o korona haplarını. Bu kadar incik cıncık edilirse hayat yaşanmaz.